Faculty
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Bittner, George
Professor in Neurobiology
E-mail Website Main Office: PAT 321
Phone: 512-471-5454 Alternate Office: PAT 315
Phone: 512-471-6971 Mailing Address:
The University of Texas at Austin
Section of Neurobiolgy
1 University Station C0920
Austin, TX 78712-1095
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Research Summary:
We research cellular/molecular mechanisms of plasmalemmal repair and nerve regeneration. That is, we examine various biophysical, biochemical, or molecular mechanisms by which lesioned neurons
repair lesions to their plasmalemma and regenerate axons. We are particularly interested in the role of calcium and axonal proteins in plasmalemmal repair and how such plasmlemmal repair relates to axonal regeneration. we are also interested in hoe polyethylene glycol (PEG) can be used to repair severed axons so that axonal continuity and function can be permanently repaired within minutes after applying PEG to rejoin severed axons.
Publications:| 2005 | Stavisky RC, Britt JM, Zuzek A, Truong E, Bittner GD., Melatonin enhances the in vitro and in vivo repair of severed rat sciatic axons., Neurosci. Lett. 376:98-101. | | 2005 | Nguyen MP, Bittner GD, Fishman HM, Critical interval of somal calcium transient after neurite transection, J. Neurosci. Res. 81:806-816. | | 2004 | S. Yoo, J.E. Bottenstein, G.D. Bittner, and H.M. Fishman., Survival of mammalian B104 cells following neurite transection at different locations depends on somal calcium concentration., J. Neurobiol. 60:137-153.. | | 2003 | R.C. Stavisky, J.M. Britt, T. Pham, T.C. Marzullo, and G.D. Bittner., Wallerian Degeneration of mammalian PNS and CNS axons is accelerated by incubation with protein synthesis inhibitors., Neuroscience Res. 47:445-449.. | | 2003 | S. Yoo, M.P. Nguyen, M. Fukuda, G.D. Bittner, and H.M. Fishman., Plasmalemmal sealing of transected mammalian neurites is a gradual process mediated by Ca-regulated proteins., J. Neurosci. Res. 74:541-551.. |
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