Enamul Huq

Huq, Enamul
Associate Professor in Molecular Cell & Developmental Biology

E-mail: huq@mail.utexas.edu

Website: http://www.sbs.utexas.edu/huq/lab

Main Office: BIO 21B
Phone: 471-9848

Alternate Office: BIO 21/22
Phone: 471-6658

Mailing Address:
The University of Texas at Austin - ICMB
1 University Station A6700
205 W. 24th St.
Austin, TX 78712-1095

Graduate Students:

  • Mulekar, Jidnyasa
  • Sharma, Nidhi
  • Zhu, Ling

    • Research Summary:
       Our research is aimed at understanding light signal transduction, specifically those pathways mediated by the phytochrome (phy) family of sensory photoreceptors that absorb light in the red and far-red region of the spectrum. The phy system, consisting of five members in Arabidopsis (phyA-phyE), controls almost every aspect of the plant life cycle including seed germination, de-etiolation and flowering time. To understand early phy signaling events, phy interacting factors, such as PIF1, have been isolated and characterized. PIF1 is a basic helix-loop-helix (bHLH) transcription factor that interacts strongly with the biologically active form of phyA and phyB. PIF1 overexpression and pif1 mutants showed defective seedling de-etiolation including, aberrant hypocotyl elongation and developmentally regulated loss of greening, suggesting that PIF1 is a key regulator of the phy-mediated control of seedling de-etiolation process. Future projects include investigating the molecular function of PIF1, identifying and functionally characterizing PIF1 interacting proteins and PIF1 target genes using biochemical, genetic and functional genomic approaches.
     
    Publications:
    Blue light induces degradation of the negative regulator Phytochrome Interacting Factor 1 to promote photomorphogenic development of Arabidopsis seedlings (2009) Genetics 182, 161-171.
    Light-induced phosphorylation and degradation of the negative regulator PIF1 depends upon its direct physical interactions with photoactivated phytochromes (2008) Plant Cell 20, 1586-1602.
    PIF1 directly and indirectly regulates chlorophyll biosynthesis to optimize the greening process in Arabidopsis (2008) Proc. Natl. Acad. Sci. USA 105, 9433-9438.
    PHYTOCHROME-INTERACTING FACTOR 1 is a critical bHLH regulator of chlorophyll biosynthesis. (2004) Science 305, 1937-1941..

     
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