David Hillis

Hillis, David
Alfred W. Roark Centennial Professor In Natural Sciences
Director, Center for Computational Biology and Bioinformatics

E-mail: dhillis@mail.utexas.edu

Website: http://www.zo.utexas.edu/faculty/antisense/

Main Office: PAT 132
Phone: (512) 471-5792

Alternate Office: PAT 133
Phone: (512) 471-5661

Mailing Address:
The University of Texas at Austin - ICMB
1 University Station CO930
2415 Speedway
Austin, TX 78712-1095
Research Summary:
   see section bio for more info
Evolutionary biology provides a conceptual framework for understanding patterns of molecular diversity. For instance, phylogenetic analyses have permeated most fields of molecular biology in recent years, from studies of the epidemiology of human immunodeficiency viruses to studies of the origin of life. Work in my lab is divided into two main areas: empirical studies of molecular evolution and the development of evolutionary theory and methodology. The empirical studies include experimental manipulation of viruses to study evolution in vitro, phylogenetic analyses of highly conserved genes, and studies of molecular processes that give rise to new genes or maintain the structure of multigene families. The theoretical and methodological work is centered on finding the best ways to estimate phylogenies from molecular sequences and on simulations of molecular evolution using supercomputers.
 
Publications:
Phylogeny of North American fireflies (Coleoptera: Lampyridae): implications for the evolution of light signals (2007) Mol Phylogenet Evol 45, 33-49.
Catchments catch all: long-term population history of a giant springtail from the southeast Australian highlands--a multigene approach (2007) Mol Ecol 16, 1865-1882.
Polyploids with different origins and ancestors form a single sexual polyploid species. (2006) American Naturalist 167, E88-E101.
Sodium channel genes and the evolution of diversity in communication signals of electric fishes: Convergent molecular evolution. (2006) Proceedings of the National Academy of Sciences USA 103, 3675-3680.

 
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