University of Texas

ICMB

Instruments

Proteomics

P/ACE 5500
(Capillary Electrophoresis)


Beckman P/ACE 5500
The P/ACE™ Series automated capillary electrophoresis (CE) systems
offer the ruggedness to operate within research, methods development and
quality control environments. These systems are application based -- optimally
configured with software, hardware and chemistry. Applications include
the analysis of basic drugs, chiral pharmaceuticals, carbohydrates, proteins,
glycoproteins and nucleic acids.

AKTA Purifier HPLC
Amersham Biosciences AKTA purifier
ÄKTA™purifier is a liquid chromatography system designed for fast and reliable separations of peptides, nucleic acids. ÄKTApurifier runs all techniques, from µg to mg scale at flow rates 0.001 ml/min – 10 ml/min and pressures 0–25 MPa. With operational simplicity and a wide range of preprogrammed application protocols and method templates.

Beckman System Gold HPLC
Beckman System Gold HPLC
HPLC
Esquire-LC Mass Spec. Bruker Daltonics Esquire-LC
The ESQUIRE-LC Ion Trap LC/MS(n) is a high performance liquid chromatograph/mass spectrometer (LC/MS) system that integrates the Agilent's 1100 Series HPLC and electrospray ionization/atmospheric-pressure chemical ionization (ESI/APCI) ion source are combined with Bruker Daltonik's multipole ion-trap MS and MS(n) analyzer. The Agilent 1100 Series LC/MSD is a benchtop mass selective detector for liquid chromatography with a choice of atmospheric pressure ionization (API) -electrospray (ES) and atmospheric pressure chemical ionization (APCI) interfaces. The system provides a solution for accurate mass measurements, peptide maps, protein identification (PID) in combination with enzymatic or chemical methods.

Symphony Quartet
Peptide Synthesizer

Ranin Symphony Quartet™
The Symphony Quartet is a four (independent) channel solid-phase synthesizer. The benefits are versatility, fast multiplex operation, low coupling cost, variable synthetic scales, automated cleavage, customizable protocols and its modular design allows the unit to be field-upgraded to a twelve channel Symphony as the synthetic needs of your lab change.
Synthesis Scale: 0.005 mM to 0.35 mM
ABI Procise 49X cLC
Protein Sequencer (Edman Chemistry)
The Applied Biosytems Procise® 49X cLC Protein Sequencing System
The Procise sequences proteins at the sub-picomole level which enables the positive identification (confidence levels > 99%) of low copy proteins in any data base. With this sensetivity almost any visibly stained spot on gel can be sequenced. Full automation allows 24/7 operation for overnight and over weekend runs.

   
   
   

Macro Molecular Interactions


Beckman Optra XL-I
Analytical Ultracentrifuge

Beckman Optra XL-I Analytical Ultracentrifuge - Solution Interaction Analysis Systems (sIA)
Because of its ability to quantitate the size and shape of macromolecules in solution, one of the most powerful methods for characterization of macromolecular interactions is Solution Interaction Analysis (sIA). The Optima™ XL-I analytical ultracentrifuge can use Scanning UV/Vis and Rayleigh Interference Optics. Sedimentation velocity or sedimentation equilibrium experiments are used to determine Stoichiometry and Shape, Equilibrium Constants, Sedimentation Coefficients, Diffusion Coefficients, and Apparent Weight Average Molecular Weights of proteins, DNA, RNA etc.
Visit the Beckman website for more information.


Dynex MLX Luminometer

Dynex MLX Microplate Luminometer
The luminometer measures chemiluminescence in solution for alkaline phosphatase or luciferase assays.
BD FACSCalibur
Flow Cytometer
Becton Dickson FACSCalibur - four-colored flow cytometer.
FACSCalibur can quickly perform routine tasks including immunophenotyping, reticulocyte enumeration, DNA analysis, and absolute counting. And with four-color analysis and sorting capabilities, FACSCalibur is a highly sensitive tool, enabling laboratories to perform sophisticated cellular work in areas such as genetics, multicolor analysis, and immune function.
For more information visit the Becton Dickson website.

BIAcore BR-1000-00
BIAcore BR-1000
Real-time BIA is a technology developed by Pharmacia Biosensor AB for monitoring biomolecular interactions in real time using a non-invasive optical detection principle based on surface plasmon resonance (SPR). The SPR response reflects a change in mass concentration at the detector surface as molecules bind or dissociate. No labeling of the interacting components is required and the technology is applicable to a wide range of experimental situations.