Richard H. Finnell , Professor, Nutritional Sciences and Chemistry and Biochemistry
 
Dr. Finnell's research examines the interaction between specific genes and environmental toxins as they influence normal embryonic development. While his primary research focuses on discovering the role of folic acid in the prevention of birth defects, his laboratory is also working to identify the gene or genes that determine susceptibility to human neural tube defects (NTDs) and orofacial clefts. Dr. Finnell is studying teratogenic agents, both pharmaceutical compounds and those found in the environment, that contribute to the population burden of birth defects.

Publications:
2013Lai, S.-C., Nakayama, Y., Sequeira, J. M., Wlodarczyk, B. J., Cabrera, R. M., Finnell, R. H., Bottiglieri, T., Quadros, E. V. , The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system, FASEB J. 27(6), p.2468-2475
2013Farkas SA, Bottiger AK, Isaksson HS, Finnell RH, Ren A and Nilsson TK, Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia, Epigenetics 8, p.303-316
2013Tabler JM, Barrell WB, Szabo-Rogers HL, Healy C, Yeung Y, Gomez Peridguero Y, Schulz C, Yannakoudakis BZ, Mesbahi A, Wlodarczyk B, Geissmann F, Finnell RH, Wallingford JB and Liu KJ. , Fuz Mutant Mice Reveal Shared Mechanisms between Ciliopathies and FGF-Related Syndromes. , Developmental Cell 25, p.623635
2013Wallingford JB, Niswander LA, Shaw GM and Finnell RH. , The continuing challenge of understanding, preventing and treating neural tube defects. , Science 339, p.1222002. DOI:10.1126/science.1222002
2011Ren A., Qiu X., Jin L., Ma J., Zhang L., Zhu H., Finnell R.H., and Zhu T, Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects. , Proc. Natl. Acad. Sci. 08(312 08(31), p.12770-12775
2009Gray RS, Abitua PB, Wlodarczyk BJ, Szabo-Rogers HL, Blanchard O, Lee I, Weiss GS, Liu KJ, Marcotte EM. Wallingford JB, and Finnell RH, The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development, Nat Cell Biol. 11(10), p.1225-1232

 
Cell and Developmental Biology Tracks and Research Focus Areas
 
Agarwala, SeemaAldrich, RichardAtkinson, Nigel
Bittner, GeorgeBratton, ShawnBrown, Richard M.
Chan, ClarenceChen, Z. JeffreyCrews, David
Croyle, MariaDalby, KevinDeLozanne, Arturo
Eberhart, Johann Ehrlich, LaurenFinkelstein, Ilya
Finnell, Richard H.Fischer, JaniceFlorin, Ernst-Ludwig
Gordon, VernitaGottlieb, EllenGross, Jeffrey
Huq, EnamulHursting, StephenJohnson, Kenneth
Jolly, ChristopherJuenger, ThomasKim, Jonghwan
Lloyd, AlanMacdonald, PaulMarcotte, Edward
Mehdy, MonaMills, Edward (Ted)Mukhopadhyay, Somshuvra (Som)
Nunez, NomeliO'Halloran, TheresaPoenie, Martin
Richburg, John HRoux, StanleyRoy, Krishnendu
Sanders, BobSchmidt, ChristineShubeita, George
Stein, DavidSuggs, LauraSullivan, Christopher
Sung, SibumUpton, JasonVandenberg, Carla
Vokes, StevenWallingford, JohnWright, Casey
Xhemalce, BlertaZhang, Xiaojing (John)

CMB Graduate Program