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Seema Agarwala
Associate Professor

Email
web site
During embryogenesis, neurons learn of their cell-fates and are assigned to specific brain nuclei (nucleogenesis), which organize brain connectivity and function. Little is known about how such complex patterni...Seema Agarwala

Richard Aldrich
Professor of Neuroscience
Karl Folkers Chair in Interdisciplinary Biomedical Research II
The National Academy of Sciences, member

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web site
Ion channels are the molecular units of electrical signaling in cells. They are proteins that regulate the movement of ions--such as sodium, calcium, and potassium--into and out of cells. They are responsible f...Richard Aldrich

Hal Alper
Assistant Professor

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web site
Our reserach focuses on engineering biology to produce biomolecules, biofuels, and pharmaceuticals using the tools of metabolic engineering and synthetic biology. The overall goal of metabolic and cellular en...Hal Alper

Eric V. Anslyn
Distinguished Teaching Professor in Chemistry & Biochemistry
Norman Hackerman Professorship in Chemistry
Email
web site
Our research is oriented at developing artificial enzymes and sensors by synthetic and combinatorial library methods. Our synthetic projects are targeted to phosphodiester hydrolysis, enolate alkylations, and ...Eric V. Anslyn

Dean Appling
Professor in Chemistry & Biochemistry
Lester J. Reed Professor In Biochemistry
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web site
My laboratory studies the organization and regulation of metabolic pathways in eukaryotes. Eukaryotic cells are composed of many different compartments, such as cytoplasm, mitochondria, and nuclei. Although ea...Dean  Appling

Nigel Atkinson
Professor in Neuroscience

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web site
Tolerance is an insidious response to an addictive drug. It causes one to consume more of the drug and and speeds the user down the path of addiction. We study the molecular mechanisms underlying drug tolerance...Nigel Atkinson

Chandrajit Bajaj
Computational Applied Mathematics Chair in Visualization
Director of Center for Computational Visualization
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web site
My research interests span the algorithmic and computational mathematics underpinnings of Structural Biology and Biophysics, Image Processing, Geometric Modeling, Computer Graphics, and Visualization. I apply t...Chandrajit Bajaj

Jeffrey Barrick
Assistant Professor, Dept. of Chemistry and Biochemistry

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web site
My laboratory uses experiments with populations of microorganisms, nucleic acids, and digital organisms to study evolution in action with the ultimate goal of harnessing evolution as a creative force for synthe...Jeffrey Barrick

Adela Ben-Yakar
Associate Professor

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web site
Dr. Ben-Yakar specializes on advanced applications of femtosecond lasers in life sciences, nonlinear microscopy, plasmonic nanoengineering, and nanotechnology. She investigates the fundamentals of femtosecond l...Adela Ben-Yakar

Halil Berberoglu
Assistant Professor in Mechanical Engineering

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web site
In my laboratory, we are interested in harnessing the power of sun through biological and artificial bio-mimetic routes for producing clean and renewable fuels. Currently we are studying algal and cyanobact...Halil Berberoglu

George Bittner
Professor in Neuroscience

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web site
We research cellular/molecular mechanisms of plasmalemmal repair and nerve regeneration. That is, we examine various biophysical, biochemical, or molecular mechanisms by which lesioned neurons repair lesions ...George Bittner

Henry Bose, Jr.
Mary M. Betzner Morrow Centennial Chair In Microbiology
Director, School of Biological Sciences
Email
web site
A long standing interest of this laboratory has been to define the mechanism of transformation by the v-rel oncogene. v-rel is the acutely transforming member of the Rel/NF-kB family of transcrip...Henry Bose, Jr.

Shawn Bratton
Associate Professor in Pharmacology and Toxicology

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web site
My laboratory focuses primarily on basic mechanisms of apoptosis (programmed cell death) and autophagy (self-cannibalism) in the context of cancer.Shawn Bratton

Richard M. Brown
Johnson & Johnson Centennial Chair In Plant Cell Biology

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web site
Cellulose is the most abundant macromolecule on earth, yet details about its biosynthesis and structure remain unclear. We are using broad, interdisciplinary advances and tools to study cellulose and its biosyn...Richard M. Brown

Karen S. Browning
Associate Professor in Chemistry & Biochemistry
Director Dual Degree MD/PhD Program
Email
web site
My research focuses on the initiation of protein synthesis in higher plants. We are seeking a molecular description of the process in which initiation factors (eIF4A, eIF4B, eIF4F, eIF3, eIF2 and PABP) select,...Karen S. Browning

James J. Bull
Johann Friedrich Miescher Regents Professor in Molecular Biology

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web site
Evolutionary genetics from the molecular to the phenotypic levels comprises the bulk of my research. Specific topics include the evolution of engineered genomes, microbial drug resistance, and adaptation addre...James J. Bull

Clarence Chan
Associate Professor in Molecular Genetics & Microbiology

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Our research is focused on two basic processes that are critical for the proliferation and well being of all eukaryotic cells - chromosome segregation (i.e., mitosis) and the spatial control of cell growth and ...Clarence Chan

Z. Jeffrey Chen
D. J. Sibley Centennial Professor in Plant Molecular Genetics

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web site
We study genetic and epigenetic mechanisms for gene expression changes in polyploids. Polyploidy, or whole-genome duplication (WGD), is an evolutionary innovation for all eukaryotes including some animals and m...Z. Jeffrey Chen

Lydia Contreras
Assistant Professor

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web site
Our research combines biomolecular engineering, genetic studies and computational modeling to understand molecular features that lead to the specific recognition and interaction of RNAs and proteins. We apply f...Lydia Contreras

David Crews
Ashbel Smith Professor of Integrative Biology, and Psychology

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web site
One of my research programs focuses on sex determination as a case study in how evolution has produced very different mechanisms for achieving the same end. Here I take advantage of the fact that in many repti...David  Crews

Maria Croyle
Professor in Pharmacy

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web site
The Anatomy of a Virus: Active Research Projects in the Croyle Lab

To date, viral vectors have held the most promise as vehicles for gene therapy because they are capable of delivering genes to certain tis...

Maria Croyle

Kevin Dalby
Associate Professor of Pharmacy, Medicinal Chemistry

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web site
Cancer is most commonly caused by the development of aberrant cell signaling pathways. Modern pharmaceutical research thus seeks a clear understanding of these pathways in efforts to treat this all too prevale...Kevin Dalby

Arturo DeLozanne
Associate Professor in Molecular Cell & Developmental Biology

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web site
We are interested in defining the molecular basis of the lysosomal disorder known as the Chediak-Higashi Syndrome. This disease is caused by mutations in a very large gene and result in the loss of a large pro...Arturo DeLozanne

John DiGiovanni
Professor and Coulter R. Sublett Chair

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Research in my laboratory has focused for many years on understanding how cancer develops and on the identification of novel targets, mechanisms and strategies for cancer prevention. Cancer is a disease involvi...John DiGiovanni

Michael Drew
Assistant Professor of Neuroscience

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A broad aim of my research is to understand how adult hippocampal neurogenesis influences learning and cognition. The work is based on growing evidence that adult neurogenesis constitutes a functionally and, pe...Michael Drew

Jaquelin Dudley
Professor of Molecular Genetics & Microbiology, Graduate Advisor

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Mouse mammary tumor virus (MMTV) is a retrovirus that induces mammary carcinomas and T-cell lymphomas in mice by insertional mutagenesis. We recently discovered a novel viral protein, Rem, which is involved in...Jaquelin Dudley

Johann Eberhart
Assistant Professor

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web site
How does a structure as complex as the vertebrate head form during development? How is variation in facial morphology generated both through evolution and in disease? Research in my lab aims at uncovering answe...Johann  Eberhart

Lauren Ehrlich
Assistant Professor of Molecular Genetics and Microbiology

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web site
T cells are master regulators of the adaptive immune system: they are essential for coordinating the appropriate immune response to different pathogens, and they are responsible for immunologic memory, which pr...Lauren Ehrlich

Ron Elber
Professor of Chemistry and Biochemistry
W.A. "Tex" Moncrief Chair in Computational Life Sciences and Biology
Email
web site
Two thrusts in computational biology are considered in the laboratory of Ron Elber in the Institute of Computational Engineering and Sciences (ICES): (i) The study of the dynamics and function of proteins and R...Ron Elber

Andy Ellington
Professor in Chemistry & Biochemistry
Wilson M. and Kathryn Fraser Research Professor In Biochemistry
Email
web site
The Ellington Lab is a biotechnology lab that engineers nucleic acids and proteins for biomedical and other applications. Nucleic acid biosensors (aptamers, ribozymes) and nucleic acid circuits (DNA computers)...Andy Ellington

Walter Fast
Associate Professor of Pharmacy, Medicinal Chemistry

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We are interested in merging emerging technologies with more classical biochemical approaches in the investigation and manipulation of various enzyme systems: 1. Quorum sensing, a “language” that some bacter...Walter Fast

Ilya Finkelstein
Assistant Professor, Dept. of Chemistry and Biochemistry

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web site
Biophysical Studies of Genome Maintenance -- Genomic DNA acts as the blueprint for life and all organisms have evolved complex protein machines that faithfully maintain our genetic material. Genomic instabi...Ilya Finkelstein

Richard H. Finnell
Professor, Nutritional Sciences and Chemistry and Biochemistry
Director, Genomic Research-Dell Children's Medical Center
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web site
Dr. Finnell's research examines the interaction between specific genes and environmental toxins as they influence normal embryonic development. While his primary research focuses on discovering the role of foli...Richard H. Finnell

Janice Fischer
Professor in Molecular Cell & Developmental Biology

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My laboratory uses Drosophila genetics and molecular biology to study universal mechanisms of development. We do most of our experiments with the Drosophila compound eye. Patterning of the Drosophila compound e...Janice Fischer

Ernst-Ludwig Florin
Associate Professor

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web site

Our long-term goal is to analyze and understand specific cellular processes from the single molecule level up to an entire cellular response. We currently investigate the molecular mechanics of microtubules,...

Ernst-Ludwig Florin

George Georgiou
Professor in Chemical Engineering
Cockrell Family Regents Chair in Engineering #9
Email
web site
Laboratory of Protein Therapeutics and Applied Immunology I was trained both in chemical engineering and in molecular biology. Throughout my career I have been studying problems related to physiology and gene...George Georgiou

Nace Golding
Associate Professor in Neuroscience

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web site
Neuronal dendrites are elaborate, tree-like structures that receive up to thousands of excitatory and inhibitory synaptic connections. The morphology and electrical properties of the dendrites strongly influenc...Nace Golding

Vernita Gordon
Assistant Professor in Physics

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Intercellular and extracellular interactions drive the formation of multicellular systems and the emergent behaviors that characterize these systems. In my group, we work to understand how cells interact with ...Vernita Gordon

Andrea Gore
Gustavus and Louise Pfeiffer Professor in Toxicology
Amer. Acad. for the Advancement of Science Fellow
Email
web site
The goal of work in the Gore Laboratory is to understand the neuroendocrine control of reproduction and sex differences in the brain during development and aging. One set of studies focuses on molecular and cel...Andrea Gore

Ellen Gottlieb
Assistant Professor in Molecular Genetics & Microbiology

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web site

A) A primary focus of our work is to decipher the molecular mechanisms governing the exciting field of RNA transport/localization. This process is of fundamental importance in development and differentiation...

Ellen Gottlieb

Jeffrey Gross
Associate Professor in Molecular Cell & Developmental Biology
Chair, Cell & Molecular Biology GSC
Email
web site
Our research focuses on vertebrate eye development utilizing the zebrafish as a model system. Combining forward genetic screens with reverse genetic and embryological manipulations we hope to understand the mol...Jeffrey Gross

Robin Gutell
Professor in Integrative Biology

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web site

The remarkable advances in Nucleic Acid sequencing and Computer technology is transforming Biology to a new level of understanding. We are now attempting to understand many biological and biochemical proces...

Robin Gutell

Marvin Hackert
Professor in Chemistry & Biochemistry
William Shive Centennial Professor In Biochemistry
Email
web site
Our research focuses on understanding function of proteins in relationship to their three-dimensional structures. Antizyme and antizyme inhibitor are regulatory proteins of ornithine decarboxylase that initiate...Marvin Hackert

Adron Harris
M. June and J. Virgil Waggoner Chair In Molecular Biology
Director, Waggoner Center for Alcohol & Addiction Research
Email
web site
This laboratory is investigating molecular mechanisms responsible for alcoholism and drug dependence. We are defining actions of alcohol and other drugs on brain cells as well as the long-term changes in gene e...Adron Harris

Rasika Harshey
Professor in Molecular Genetics & Microbiology

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web site
We have two major research interests: DNA transposition and Bacterial Signaling & Motility. (1) DNA transposition is central to the propagation of phage Mu (our model system) as it is to retroviruses. The integ...Rasika Harshey

Arjang Hassibi
Assistant Professor

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web site
Dr. Hassibi's research focuses on new approaches to sense, detect and analyze biological systems using integrated systems and advanced signal processing techniques. In particular, he is interested in CMOS-based...Arjang  Hassibi

Christine Hawkes
Associate Professor

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Research in the Hawkes Lab is focused on a mechanistic understanding of how plant-microbe interactions affect community and ecosystem processes. We explore how these relationships are influenced by alterations ...Christine Hawkes

David L. Herrin
Professor of Molecular Cell & Developmental Biology

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Most of our research revolves around the chloroplast genome of plants and algae, which we view as a simpler model genome (compared to the nucleus) for understanding genome expression, regulation, and evolution....David L. Herrin

David Hillis
Alfred W. Roark Centennial Professor In Natural Sciences
Director, Center for Computational Biology and Bioinformatics
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web site
Evolutionary biology provides a conceptual framework for understanding patterns of molecular diversity. For instance, phylogenetic analyses have permeated most fields of molecular biology in recent years, from ...David Hillis

David Hoffman
Associate Professor in Chemistry & Biochemistry

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web site
Biophysical methods such as nuclear magnetic resonance (NMR) spectroscopy and x-ray crystallography are extensively used in our investigations of protein and RNA structure and function. Current work includes t...David Hoffman

Hans A. Hofmann
Associate Professor
ICMB Fellow
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web site
The research in Dr. Hofmann's laboratory seeks to understand the molecular and hormonal mechanisms that underlie social behavior and its evolution. African cichlid fishes are an ideal model system to address th...Hans A. Hofmann

Lin Huffman
Graduate Student

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Jon Huibregtse
Professor in Molecular Genetics & Microbiology
Graduate Advisor, Cell and Molecular Biology Graduate Program
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web site
The Huibregtse lab studies the biochemistry of the ubiquitin proteolysis system, a major pathway for degradation of proteins in eukaryotic cells. Our interest in this pathway arose from study of human papilloma...Jon Huibregtse

Enamul Huq
Associate Professor in Molecular Cell & Developmental Biology

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web site
Our research is aimed at understanding light signal transduction, specifically those pathways mediated by the phytochrome (phy) family of sensory photoreceptors that absorb light in the red and far-red region o...Enamul Huq

Stephen Hursting
Professor and Margaret McKean Love Chair, Division of Nutritional Sciences

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Research Interests: Diet-gene interactions relevant to cancer prevention, particularly the molecular and hormonal mechanisms underlying energy balance-cancer associations. Focus Areas: 1. Mechanism-Based N...Stephen Hursting

Brent Iverson
Distinguished Teaching Professor in Chemistry & Biochemistry
Warren J. and Viola Mae Raymer Professor
Email
web site
Antibody and enzyme engineering with an emphasis on creating better methods for improving protein function for therapeutic applications. Several new technologies have been developed and patented. Recent success...Brent Iverson

Vishwanath Iyer
Professor in Molecular Genetics & Microbiology

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web site
Nearly all cells respond to physiological or developmental cues by large-scale transcriptional reprogramming – altering the expression of hundreds to thousands of genes throughout the genome. Such sweeping chan...Vishwanath Iyer

Robert Jansen
Sidney F. and Doris Blake Centennial Professor In Systematic Botany and the Blake Collection

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My primary research interests involve the determination of phylogenetic relationships among plants and the evolution of the chloroplast genome. Research in my lab is concentrated in three areas: (1) organizati...Robert Jansen

Makkuni Jayaram
Professor in Molecular Genetics & Microbiology

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web site

We study the molecular mechanisms by which extrachromosomal DNA elements maintain themselves stably and at relatively high copy numbers without endangering their host organisms. The model system we employ i...

Makkuni Jayaram

Arlen Johnson
Professor In Molecular Genetics and Microbiology, Under Graduate Advisor

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Since working out the pathway for nuclear export of the large ribosomal subunit more than 10 years ago, we have continued to study both nuclear and cytoplasmic events of making ribosomes (Lo et al Mol Cell, 201...Arlen Johnson

Kenneth Johnson
Professor in Chemistry & Biochemistry
Roger J. Williams Centennial Professor In Biochemistry
Email
web site
Three polymerases and a molecular motor: In projects related to AIDS, we examine HIV reverse transcriptase mechanism, its resistance to nucleoside analogs, and characterization of novel nonnucleoside inhibitor...Kenneth Johnson

Daniel Johnston
Director; Ctr for Learning and Memory, Institute for Neuroscience
Chairman, Section of Neurobiology
Karl Folkers Chair in Interdisciplinary Biomedical Research

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web site

Research in my laboratory is primarily directed towards understanding the cellular and molecular mechanisms of synaptic integration and long-term plasticity of neurons in the medial temporal lobe. We have ...

Daniel Johnston

Christopher Jolly
Assistant Professor in Nutritional Sciences

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My lab focuses on understanding the biochemical/molecular mechanisms underlying reduced immune function in aging. We primarily focus on identifying signaling pathways which may lead to changes in lipid metabol...Christopher Jolly

Thomas Juenger
Associate Professor, Integrative Biology
Ph.D.
Email
web site
My research focuses on the interface of ecological and evolutionary processes in natural plant populations. I am generally interested in phenotypic evolution, and have studied a number of systems over the cours...Thomas Juenger

Adrian Keatinge-Clay
Assistant Professor in Chemistry & Biochemistry

Email
Many important pharmaceuticals, including the antibiotic erythromycin and the immunosuppressant rapamycin, belong to a diverse class of molecules called polyketides. My lab uses protein crystallography and enzy...Adrian Keatinge-Clay

Sean Kerwin
Associate Professor in Pharmacy
G. D. Searle Fellow
Email
web site
The long-term goal of our research is the development of selective strategies for the treatment of cancer, inflammation, and infectious diseases. Our work takes place at the interface of computational chemistr...Sean Kerwin

Jonghwan Kim
Assistant Professor in Molecular Cell and Developmental Biology

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web site
Defining the molecular mechanisms maintaining stemness - self-renewal and pluripotency - of Embryonic stem (ES) cells, as well as induced pluripotent stem (iPS) cells is of great interest for understanding earl...Jonghwan Kim

G. Barrie Kitto
Professor in Chemistry & Biochemistry

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web site

(1) Development of treatments and vaccines for AIDS. This research includes both the use of immunotoxins targeted to infected cells and a novel class of MHC-based vaccines.

(2) Vaccines for Respirato...

G. Barrie Kitto

Kimberly Kline
Julian C. Barton Professor in Nutrition

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web site
Research interests are in the interdisciplinary areas of nutrition and cancer biology. Long term goals are to better our understanding of the biological actions of vitamin E, both naturally occurring forms and ...Kimberly Kline

Robert Krug
Chair, Molecular Genetics and Microbiology,
Lorene Morrow Kelley Fellow In Microbiology
Email
web site
The major focus of the Krug laboratory is the molecular biology of human influenza viruses (influenza A and B viruses), which cause widespread human disease. We are determining the molecular mechanisms of viral...Robert Krug

Alan M. Lambowitz
Mr. & Mrs. A. Frank Smith, Jr. and Nancy Lee & Perry R. Bass Regents Chairs In Molecular Biology
Director, Institute for Cellular and Molecular Biology
Email
web site
Our laboratory studies gene expression, RNA splicing, mobile self-splicing introns, and retroviral-like genetic elements in eukaryotes and prokaryotes. We are interested in mechanisms by which mobile introns pr...Alan M. Lambowitz

Seongmin Lee
Assistant Professor

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The unifying theme of the Lee lab is the elucidation of molecular mechanisms underlying genome/epigenome management using toolkits of biochemistry, chemical and structural biology. In particular, we are interes...Seongmin Lee

Hung-wen (Ben) Liu
George H. Hitchings Regents Chair In Drug Design
Professor of Medicinal Chemistry, Chemistry, and Biochemistry
Email
web site

My group is currently working on three general areas with the focus aimed at the elucidation of the mechanisms of novel enzymatic reactions and the design of methods to control and/or regulate their function...

Hung-wen (Ben) Liu

Alan Lloyd
Professor in Molecular Cell & Developmental Biology

Email

The main goal of my lab is to understand developmental mechanisms and pigment pathways in plants. The control of cell fate decisions is a central issue during plant development and pattern formation. One mai...

Alan Lloyd

Paul Macdonald
Mr. and Mrs. Robert P. Doherty, Jr. Regents Chair In Molecular Biology

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Regulation of gene expression at the post-transcriptional level has long been recognized for its essential role in early development, and has more recently emerged as a widespread phenomenon affecting the major...Paul Macdonald

Dmitrii Makarov
Associate Professor in Chemistry & Biochemistry

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web site

Our work in single molecules theory is motivated by the recent developments in scanning tunneling microscopy, atomic force microscopy, and single molecule optical spectroscopy, which enable experimenters to ...

Dmitrii Makarov

Edward Marcotte
Professor in Chemistry & Biochemistry
Mr. & Mrs. Corbin J. Robertson, Sr. Regents Chair in Molecular Biology
Email
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We work in the field of systems and synthetic biology, studying the large-scale organization of proteins. Essentially, we try to reconstruct the 'wiring diagrams' of cells, learning how all proteins encoded by ...Edward Marcotte

Mia Markey
Associate Professor in Biomedical Engineering

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The mission of the Biomedical Informatics Lab (BMIL) is to design cost-effective, computer-based decision aids. The BMIL develops decision support systems for clinical decision making and scientific discovery u...Mia Markey

Stephen Martin
Professor in Chemistry & Biochemistry
M. June and J. Virgil Waggoner Regents Chair In Chemistry
Email
web site
The design and synthesis of small molecules that exhibit high affinities for biomacromolecules is critical to the study of enzyme mechanism and specificity and to correlating structure and function in protein-l...Stephen Martin

Andreas Matouschek
Professor in Molecular Genetics and Microbiology

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Andreas earned his first degree in biology at the Ludwig Maximilians University Munich and a Ph.D. with Alan Fersht in the chemistry department of the University of Cambridge. He then did a postdoc with Jeff S...Andreas Matouschek

Mikhail Matz
Assistant Professor, Integrative Biology

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web site
We are an ecological genomics lab working predominantly with reef-building corals. Our main research projects are: (1) Adaptive genetic variation in reef-building corals. We use genetics and genomics to disc...Mikhail Matz

Jennifer Maynard
Assistant Professor of Chemical Engineering

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Building on decades of basic research in the biological sciences, fundamental principles underlying the function of complex biological systems are being elucidated in laboratories throughout the world. Concurre...Jennifer Maynard

Mona Mehdy
Associate Professor in Molecular Cell & Developmental Biology

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In response to pathogens and herbivores, plants employ up-regulation and down-regulation of diverse genes to achieve resistance. Research in my lab centers on two areas: 1) molecular mechanisms of down-regula...Mona Mehdy

Lauren Ancel Meyers
Professor

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web site
The Meyers lab works on problems at the interface of evolution and epidemiology. We are simultaneously pursuing projects in two areas. They are applying network theory, agent-based simulation, and other qua...Lauren Ancel Meyers

S. John Mihic
M. June and J. Virgil Waggoner Fellow In Molecular Biology
Associate Professor
Email
web site
Research in my laboratory is focused on characterizing the molecular mechanisms of action of alcohol, inhaled solvents and anaesthetics on ligand-gated ion channels. We combine receptor subunit mutagenesis with...S. John Mihic

Kyle Miller
Assistant Professor of Molecular Genetics and Microbiology

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DNA damage represents a formidable challenge to genome maintenance. To protect our genetic material, our cells have evolved multifaceted systems, collectively termed the DNA damage response (DDR), to detect and...Kyle Miller

Edward (Ted) Mills
Associate Professor

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web site
The broad focus of our research group is to define the molecular pathways that regulate aging and age-related diseases. In diverse organisms ranging from worms to mammals, the overconsumption of food dramatic...Edward (Ted) Mills

Daniel Miranker
David Bruton Jr Centennial Fellow in Cs #3, PHD

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web site
Professor Miranker’s research group addresses biological database infrastructure with applications in Proteomics, Genomics and Phylogeny. One research focus concerns search and mining methods for large-scale ...Daniel Miranker

Ian Molineux
Professor in Molecular Genetics & Microbiology

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Our major interest is understanding how nucleic acids pass through lipid bilayers. Our model system is bacteriophage T7, which uses three different motor proteins to transport its DNA into the cell at the in...

Ian Molineux

Nancy Moran
Professor

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web site
Symbioses between animals and microbes have evolved many times, and have been a major influence on macroevolutionary patterns of diversification as well as short-term evolution within host populations. My lab g...Nancy Moran

Hitoshi Morikawa
Associate Professor in Neuroscience
M. June and J. Virgil Waggoner Fellow In Molecular Biology
Email
web site
A large amount of knowledge has accumulated over the past decades implicating the central dopaminergic system in reward-based reinforcement learning, decision making, motivation and locomotion, as well as its d...Hitoshi Morikawa

Richard Morrisett
Professor in Pharmacy

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web site
My primary research interests center upon the interactions between excitatory and inhibitory neurotransmitters and their synaptic and cellular effects that regulate certain aspects of normal neural function as ...Richard Morrisett

Somshuvra (Som) Mukhopadhyay
Assistant Professor

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We study intracellular membrane trafficking in the context of normal cell physiology and human disease. Transport of proteins and lipids between membrane bound subcellular organelles is essential for life. Cel...Somshuvra (Som) Mukhopadhyay

Hiroshi Nishiyama
Assistant Professor in Neuroscience

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web site
The synaptic connections between neurons undergo continuous structural remodeling even in the adult brain. However, we still have not largely understood the structural plasticity of neural circuitry in the con...Hiroshi Nishiyama

Nomeli Nunez
Assistant Professor in Human Ecology

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Dr. Nomeli Nunez earned a bachelor's degree in biology in 1992 at the University of California-Santa Cruz, where he was an MBRS program participant. He finished his Ph.D. in pharmacology and toxicology at W...Nomeli Nunez

Theresa O'Halloran
Associate Professor in Molecular Cell & Developmental Biology

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The membranes of eukarytoic cells are in continual flux, trafficking receptors and other proteins to their appropriate intracellular destinations. This process is important to signal transduction, cancer, and ...Theresa O

Howard Ochman
Professor

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We apply experimental, comparative and computational approaches to investigate the factors contributing to the evolution of bacterial genomes and microbial communities. Some of our current projects investigate:...Howard Ochman

Tanya Paull
Professor in Molecular Genetics & Microbiology
Howard Hughes Medical Institute Investigator
Email
web site

Research in the lab is focused on the DNA damage response in eukaryotic cells, specifically the checkpoint activation and DNA repair responses that occur immediately after the introduction of chromosomal dou...

Tanya Paull

Shelley Payne
Professor of Molecular Genetics & Microbiology
University Distinguished Teaching Professor
Email
web site
We are interested in the genetics and regulation of virulence factors of gram negative pathogens, including Shigella and Vibrio cholerae. Members of the Shigella species are found both extracellularly and int...Shelley Payne

Steven Phelps
Associate Professor

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web site
The lab employs a diverse array of approaches, ranging from computational models to the molecular analysis of gene expression. This work is strongly anchored in empirical studies of animal behavior in both the ...Steven Phelps

Jon Pierce-Shimomura
Assistant Professor of Neuroscience

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web site
We are currently focused on two issues: 1) What are the underlying causes and potential cures for Down syndrome and Alzheimer's disease? We hope to help create the first medicines that effectively treat ind...Jon Pierce-Shimomura

Martin Poenie
Associate Professor in Molecular Cell & Developmental Biology

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We are interested in the cell biology of T cells and how they carry out their effector functions. In particular we are want to know how signaling events lead to reorganization of the T cell cytoskeleton and tra...Martin Poenie

William Press
Professor of Computer Sciences and Integrative Biology
Warren J. and Viola M. Raymer Chair
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web site
My work is in computational biology, especially whole-genome studies. My collaborators and I develop and test new algorithms for finding and characterizing functional sequence, and for understanding evolutiona...William  Press

Nicholas Priebe
Assistant Professor in Neuroscience

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web site
The massive expansion of cerebral cortex is a hallmark of the human brain. We know that the cortex plays an essential role in our perceptions and actions. Sensory inputs from the periphery are transformed in ...Nicholas Priebe

Kimberly Raab-Graham
Assistant Professor of Neuroscience

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My current research has focused on identifying synaptic mRNAs and developing tools to characterize the local translation of these transcripts. I now plan to use these tools to address the questions of what mRNA...Kimberly Raab-Graham

Pengyu Ren
Assistant Professor

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Dr. Ren studies the structure and function of biomolecules, with pharmaceutical and biomedical applications. Ren’s research team uses a range of computational tools to study the structure, dynamics and interact...Pengyu Ren

John H Richburg
Professor
Head, Division of Pharmacology and Toxicology
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The broad focus of my research is the investigation of the mechanism(s) by which environmental toxicants affect male reproduction. My specific research interests are directed towards thee understanding of the s...John H Richburg

Austen Riggs
Professor Emeritus

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Interactions between and within macromolecular assemblages are frequently the key to understanding many complex cellular processes. I am particularly interested in the molecular mechanisms responsible for pr...Austen Riggs

Jon Robertus
Professor in Chemistry & Biochemistry
Benjamin Clayton Centennial Professor In Biochemistry
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Research in my laboratory focuses on protein structure, action, engineering and rational drug design. This includes analysis of three-dimensional structure by X-ray crystallography, site-directed mutation of cl...Jon Robertus

Stanley Roux
Professor in Molecular Cell & Developmental Biology

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We are studying how the stimuli of light and gravity alter patterns of plant development. In our studies of light-induced responses we have found that ectoapyrase, an enzyme whose expression is strongly regulat...Stanley Roux

Krishnendu Roy
Associate Professor in Biomedical Engineering

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My overall research interest is in developing novel concepts for polymer controlled delivery of biological factors, especially for nucleic acid therapeutics (DNA, SiRNA and oligos) and stem cell engineering...

Krishnendu Roy

Rick Russell
Associate Professor in Chemistry & Biochemistry

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Our group combines biochemical and biophysical approaches to study the processes of RNA folding and assembly with proteins. Some of nature’s most complex and important enzyme machines are composed of RNA and pr...Rick Russell

Bob Sanders
Professor in Molecular Genetics & Microbiology

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Research interests are in the interdisciplinary areas of nutrition and cancer biology. Long term goals are to develop vitamin E analogs as anticancer agents, and to increase the understanding of the biological...Bob Sanders

Sara Sawyer
Assistant Professor of Molecular Genetics and Microbiology

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Evolutionary changes driven by historical viral epidemics have left a molecular fossil record in our DNA sequence. Our goal is to learn about natural strategies that have been successful at beating viruses in t...Sara Sawyer

Christine Schmidt
Adjunct Professor

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Damage to spinal cord and peripheral nerve tissue can have a devastating impact on the quality of life for individuals suffering from nerve injuries. Many attempts are being made to engineer therapies that can...Christine Schmidt

Jason Shear
Professor in Chemistry & Biochemistry

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The Shear Group investigates complex cellular and biochemical microenvironments at a variety of levels. Several current projects are focused on development of novel sensor- array methods and electrophoretic a...Jason Shear

George Shubeita
Assistant Professor

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Our group is interested in unraveling molecular mechanisms that regulate molecular-motor-driven transport within cells. We combine biophysical, biochemical, genetic and cell biology techniques to decipher the r...George Shubeita

David Stein
Professor in Molecular Cell & Developmental Biology

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Most of the research in our lab is focused on the question of how a complex multicellular organism develops from a seemingly simple single cell, the fertilized Drosophila egg. In one set of investigations, we a...David Stein

Scott Stevens
Associate Professor of Molecular Genetics & Microbiology, Chair of Graduate Studies Committee

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Ribonucleoproteins (RNPs) function in many cellular processes and the malfunction of some of these RNPs cause serious human disease. To better understand how disease states can be corrected, our laboratory stud...Scott Stevens

Laura Suggs
Assistant Professor of Biomedical Engineering

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Our lab is primarily interested in the development of biologically active materials and their use and behavior in cardiovascular tissue engineering. It is important to understand molecular and cellular mech...

Laura Suggs

Christopher Sullivan
Associate Professor in Molecular Genetics and Microbiology

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The discovery of RNA interference (RNAi) and small regulatory RNAs such as siRNAs and miRNAs, has dramatically changed our understanding of the regulation of gene expression. Consequently, RNAi has generated mu...Christopher  Sullivan

Sibum Sung
Assistant Professor Cell and Developmental Biology

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Our research interests focus on the genetic, molecular and biochemical understandings of plant development through plant-environment interactions. We are particularly interested in the epigenetic regulation of...Sibum Sung

Wesley Thompson
Professor

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My lab is interested in the role of glial cells in the formation and maintenance of synapses in the nervous system. For this purpose we study the simplest of all synapses, the neuromuscular junction where our ...Wesley Thompson

M. Stephen Trent
Professor in Molecular Biosciences

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In order to survive, bacteria must quickly respond to changes in the surrounding environment. We are interested in how diverse environmental stimuli promote changes in conserved microbial structures found on t...M. Stephen  Trent

Haley Tucker
Marie Betzner Morrow Centennial Chair and Professor of Cellular and Molecular Biology

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We hope to better understand transcriptional regulation of hematopoetic and cardiovascular development and function in normal and diseased mice. Ongoing projects can be grouped operationally under four transcr...Haley Tucker

Jason Upton
Assistant Professor in Molecular Genetics & Microbiology

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Programmed cell death (PCD) serves as an efficient intrinsic defense against cellular injury or infection. Many pathogens, such as viruses, subvert normal cell death pathways as a mechanism to facilitate th...

Jason Upton

Carla Vandenberg
Associate Professor

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My lab has had a long-standing interest in JNKs (c-Jun N-terminal Kinases), kinases traditionally characterized as a pro-apoptotic enzyme and necessary for many therapeutic drugs to induce cell death. Recent s...Carla Vandenberg

Karen M. Vasquez
Professor
Fellow of Coulter R. Sublett Chair in Pharmacy
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Our research efforts are focused in three general areas within an overall theme of genome instability, DNA damage and mechanisms of repair. A unique feature of our approach is an emphasis on the role of DNA str...Karen M. Vasquez

Steven Vokes
Assistant Professor in Molecular Cell & Developmental Biology

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We are interested in understanding how cells integrate information in a way that directs them to make appropriate decisions. Our research specifically focuses on understanding how cells respond to secreted Hedg...Steven Vokes

James Walker
Professor in Molecular Genetics & Microbiology

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My research interests include the mechanism by which the bacterial chromosome is replicated, how replication is controlled, and how replication is integrated with cell division. Specifically, we study compon...

James Walker

John Wallingford
Associate Professor in Molecular Cell & Developmental Biology

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The process by which embryos acquire their final shape involves the coordination of cell fate decisions with cell movement. We are taking an integrated approach to understanding this process in vertebrate embr...John Wallingford

Tandy Warnow
Professor in Computer Sciences

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Phylogenies (i.e. evolutionary trees) are fundamental to our understanding of evolution, and their inference is a major part of research in many areas of biology. With the production of increasing amounts of b...Tandy Warnow

Lauren Webb
Assistant Professor in Chemistry & Biochemistry

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Research in the Webb group seeks to understand and manipulate the mechanisms of interaction, organization, and self-assembly of biological macromolecules that lead to the complex and emergent properties of livi...Lauren Webb

Marvin Whiteley
Professor

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Bacteria exhibit many social activities and represent a model for dissecting social behavior at the genetic level (recently defined as sociomicrobiology). One example of social behavior in bacteria is the use o...Marvin Whiteley

Christian Whitman
Professor in Pharmacy, Medicinal Chemistry
Romeo T. Bachand, Jr. Regents Professorship In Pharmacy
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Our research focuses on mechanistic, kinetic, and structural studies of the enzymes involved in the bacterial degradation of aromatic and halogenated compounds. One goal is to better understand the relationship...Christian Whitman

Claus Wilke
Professor in Integrative Biology

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I am a computational biologist. I use bioinformatical and statistical methods to analyze biological data sets, in particular whole-genome and high-throughput data sets; I also develop mathematical models and...

Claus Wilke

Casey Wright
Assistant Professor

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My laboratory is focused on unraveling the complex regulatory mechanisms that govern the activity of the pleiotropic transcription factor nuclear factor-kappaB (NF-kB), with the long-term goal of identifying ph...Casey Wright

Blerta Xhemalce
Assistant Professor

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The Xhemalce lab aims to decipher how epigenetic modifications modulate the molecules that mediate the expression of genetic information from DNA to RNA to proteins, with a particular focus on the microRNA path...Blerta Xhemalce

Harold Zakon
Professor in Neuroscience

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Ion channels are fundamental for the workings of the nervous system. We study the function, regulation, and evolution of voltage-dependent ion channels. Our main focus has been to study the regulation of sodium...Harold Zakon

Boris Zemelman
Assistant Professor of Neuroscience

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We strive to understand the role of hippocampus in memory formation by manipulating its functional elements, namely the assemblies of cells that carry out particular tasks. This objective raises four practical ...Boris Zemelman

Yan Jessie Zhang
Assistant Professor in Chemistry & Biochemistry

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A major focus of Zhang's research is the elucidation of the fundamental principles of transcriptional regulation. The primary experimental approaches used in the laboratory are macromolecular structure determi...Yan Jessie Zhang

Xiaojing (John) Zhang
Assistant Professor in Biomedical Engineering

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Our current research focus is on the development of miniature tools with which to describe cellular processes quantitatively. Using these novel cell-machine interfaces, we can investigate, with extremely high s...Xiaojing (John) Zhang

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